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ISSN 1995-5537

2 2010

«Biotechnology» journal, Vol. 3, No. 2, 2010
Р. 89-95, Bibliography. 15, Russian..
Universal Decimal classification: 615.32.451.16 + 638.178

Institute for Problems of Cryobiology and Cryomedicine of National Academy of Sciences of Ukraine, Kharkіv;
Institute of Chemistry at V. N. Karazin, Kharkіv National University, Kharkіv
Chemical composition of an extract derived from dead bee bodies (apiextract) was studied. The extraction procedure was optimized, chemical composition and antioxidant activity depending on the extraction conditions were estimated. It has been shown that apiextract is a valuable source of biologically active compounds: vitamins, amino acids, and antioxidants. Antioxidant activity of the apiextract is highly competitive to ones of traditional pharmaceutical preparations. It was established that the maximum extract yield is achieved after 25–30 extraction cycles when using 150 ml ethanol per 10 g of raw material, moreover purification of both initial raw material and the extract itself from admixtures results in a reduction of its biological activity, therefore it is not desirable.

Key words: extraction, dead bee bodies, apiextract, antioxidant activity.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2010