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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)


Ж-л "Biotechnologia Acta" Т. 14, № 1 , 2021
С. 46-56, библиогр. 61, англ.
УДК: 579.61 + 616.34-008.87


Bakalchuk M. M., Besarab O. B.

National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”

Fecal microbiota transplantation (FMT) is a treatment method based on donor's fecal solution injection into the patient's gastrointestinal tract. FMT is effectively used in the treatment of recurrent Clostridium difficile infection. There is also growing interest in the therapeutic application of the method to treat metabolic, autoimmune and other disorders that was not previously associated with intestinal microbiota. Despite the promising results of FMT use, the organizational and legal matters and that of the safety FMT application have not yet been resolved in the European and Ukrainian medical community. The purpose of this review was to summarize information on the FMT application and the regulatory aspects of its use. The analysis of the practical instructions provisions of for FMT applying in clinical practice was carried out, and the bioethical problems associated with the FMT use were investigated.

Key words: intestinal microbiota, fecal microbiota transplantation, Clostridium difficile, inflammatory bowel disorder.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2021