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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

 1 2014

"Biotechnologia Acta" v. 7, no 1, 2014
Р. 100-109, Bibliography 18, Ukrainian
Universal Decimal classification: 541.18:542.8:577.352


Voitenko O. Yu., Podolska V. I., Gryshchenko N. I., Ulberg Z. R., Yakubenko L. M.

Ovcharenko Institute for Biocolloidal Chemistry of National Academy of Sciences of Ukraine, Kyiv

The antimicrobial properties of complex materials containing ultradispersed silver particles directly formed in the Candida albіcans, Escherichia сolі, Pseudomonas fluorescens, and Bacillus cereus cell walls were investigated. Complex material based on pseudomonas was more active against gram-positive bacteria, the yeast like fungi based material was mainly active against colibacillus. After a cell-matrix treatment in a hypertonic solution or by acid hydrolysis, the antimicrobial properties of complex materials increased by 20—40%. In a liquid-phase medium, the complex materials with incorporated silver particles in composition with antibiotics strengthened anti-microbial properties of chloramphenicol, tetracycline and amoxiclav antibiotics with respect to E. faecalis, as well as penicillin antibiotics (ceftriaxone, cefotaxime, amoxicillin, amoxiclav) against E. coli. The obtained data can serve as a basis for development of the new antibacterial and fungicide cells based materials impregnated with ultradispersed substances.

Key words: complex materials, ultradispersed silver particles, antibacterial effect.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2014


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