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ISSN 1995-5537

3  2008

“Biotechnology” journal Vol. 1, No. 3, 2008
Р. 13-23, Bibliography 80, Ukrainian.
Universal Decimal classification 577.152.34:577.151.5

Institute of Microbiology and Virology of National Academy of Sciences of Ukraine, Kyiv

Microbial collagenolytic enzymes are able to hydrolyze such a hard insoluble protein substrate as collagen. In this article are gathered data concerning the ability to degrade collagen amongst various groups of microorganisms, such as bacteria, fungi, actinomycetes and yeasts. The physical and chemical properties of collagenolytic enzyme preparations and methods of their separation and purification have been examined. The possible application ways of these enzymes in industry and medicine have been discussed.

Key words: microbial collagenolytic enzymes, physical and chemical properties, methods of isolation and purification, practical application.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008