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SSN 2410-7751 (Print)
ISSN 2410-776X (Online)

4 2019

"Biotechnologia Acta" V. 12, No 4, 2019
Р. 5-18, Bibliography  47, English
Universal Decimal Classification: 579.663


Pirog T. P., Kliuchka I. V., Kliuchka L. V.

National University of Food Technologies, Kyiv

This review summarizes the published data and own results concerning synergism of antimicrobial activity of essential oils with antibiotics against bacteria of the family Enterobacteriaceae, genera Staphylococcus, Pseudomonas, Acinetobacter; with synthetic antifungal drug fluconazole, against yeast genus Candida; with surfactants of microbial origin, against bacterial and yeast test cultures. The synergistic effect of the complex of essential oils with antibiotics, enzymes, surfactants, etc. on biofilms was considered as well. Mixing essential oils with other biocides allowed to significantly decrease the minimum inhibitory concentrations of each component. The probability of emerging resistance to antibiotics is also reduced in the pathogenic bacteria and yeasts due to the antimicrobial action of essential oils that caused the dysfunction of cellular membrane of microorganisms. The prospects of implementing complex essential oils with antibiotic nisin in the food industry, and with other antibiotics in veterinary medicine are discussed.

Key words: essential oils, antimicrobial compounds, synergism of antimicrobial action, destruction of biofilms.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2019