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ISSN 1995-5537

4 2011

"Biotechnology" journal V. 4, No. 4, 2011
Р. 9-19, Bibliography 41, Ukrainian.
Universal Decimal classification: 577 (087.1 + 112.4)

CLUSTERS FROM A FEW SILVER ATOMS
IN FLUORESCENT SENSORY TECHNOLOGIES

O. P. Demchenko, M. I. Kanyuk

Palladian Biochemistry Institute of National Academy of Sciences of Ukraine, Kyiv

Clusters out of several silver atoms possess unique optical properties that allows considering them as efficient substitutes to organic dyes in different fluorescente sensor technologies. The properties of these clusters and examples of their applications, techniques of synthesis and stabilization in different macromolecular and low-molecular matrices were described. In particular, the methods of cluster obtaining with chemical reducing agents, as well as the recovery in response to light were very simple.

Application of silver clusters for DNA labeling and a DNA-sensors creating were demonstrated on the basis of their hybridization followed by cluster fluorescence detection. Other prospective areas of application developed extremely fast, including ion detection and living cell labeling, both in terms of basic research and in view of ample opportunities for practical application.

Key words: fluorescence, clusters of atoms of silver, sensory technologies.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008