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ISSN 1995-5537

1 2008

“Biotechnology” journal Vol. 1, No. 1, , 2008
Р. 74-78, Bibliography 14, Russian
Universal Decimal classification: 577.21:578.81:579.812.24

F. I. Tovkach

Institute of Microbiology and Virology of National Academy of Sciences of Ukraine, Kyiv

 For the first time the perspective of biotechnological system for synthesis of microbial products based on Erwinia carotovora, its bacteriophages and plasmids is observed. This system is based on three fundamental principals: gene expression included in multicopy prophage element pCA25 and its analogies, the influence of prophage’s genes on type II secretion system and products translocation outside the cell after their supersynthesis.

It is supposed that this system would be economical, ecologycaly safed and harmless for human’s health and also will permitt to acquire practicaly pure protein products.

Key words: Erwinia carotovora, autonomous genetic elements, bacteriophages, plasmides, biotechnological system.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008