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Home Archive 2008 № 1 ESTIMATION OF EFFECTIVENESS OF EXPERIMENTAL DEVICE FOR OBTAINING OF TYPE I INTERFERONS Yu. M. Penchuk, O. V. Karpov V. M. Povodzinsky S. V. Veriovka, Z. R. Ul’berg
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ISSN 1995-5537

Scientific journal

БІОТЕХНОЛОГІЯ

V. 1, No. 1, 2008


“Biotechnology” journal Vol. 1, No.1, 2008
P. 80-84, Bibliography 14, Ukrainian.
Universal Decimal classification: 578.245:577.1113.7:57.086.833

 

ESTIMATION OF EFFECTIVENESS OF EXPERIMENTAL DEVICE

FOR OBTAINING OF TYPE I INTERFERONS

Yu. M. Penchuk, O. V. Karpov V. M. Povodzinsky S. V. Veriovka, Z. R. Ulberg

National Universyti of Food Technologies, Kyiv
Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, Kyiv
Kolomiychenko Institute of Otolaringology of Academy of Medical Sciences of Ukraine, Kyiv
Ovcharenko Institute of Biocolloid Chemisrty
Ovcharenko Institute of Biocolloid Chemisrty of Nationale Academy of Sciences of Ukraine, Kyiv

The authors describe an experimental device with computer assisted action for cell cultivation and induced type I interferon (IFN) synthesis. The device is based on the use of previously elaborated particles bearing an immobilized complex inductor of repeated action.

The device is shown to be effective for cultivation of both monolayer and suspended cells producing the IFN. Physiological conditions of both cell types cultivation are investigated. The authors conclude their device to be useful for obtaining of biologically active substances by this technology.

Key words: interferon, inductor, immobilization, cpheron, cell culture, roller cultivation, mononuclears.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008

 

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Home Archive 2008 № 1 ESTIMATION OF EFFECTIVENESS OF EXPERIMENTAL DEVICE FOR OBTAINING OF TYPE I INTERFERONS Yu. M. Penchuk, O. V. Karpov V. M. Povodzinsky S. V. Veriovka, Z. R. Ul’berg

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